Inno-Lia® HIV I/II Score (20T)
The clearest answer in HIV confirmation. Line immunoassay for the confirmation and discrimination of antibodies to HIV-1, HIV-1 group O and HIV-2 in human serum and plasma.
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Description
Features and Benefits
- All major HIV strains detectable with one strip: HIV-1, HIV-2, and HIV-1 group O
- Optimal specificity in screened-negative blood donors: 96.7% (290/300)
- High sensitivity in BBI panels
- Short and overnight procedures
- Color-coded reagents
- Ready-to-use reagents
- Four control lines to monitor 1) non-specific reactivity, 2) sample addition, 3) and 4) color development steps
- Fully automated strip processing possible using TENDIGO™, Auto-LIA™ 48, Auto-LiPA™ 48 or AutoBlot 3000(H)
- Objective, automated reading and interpretation of the strips possible using LiRAS® for Infectious Diseases
Art. no. 80540 (20T - CE) - Please contact your local Fujirebio representative for the availability of this product in your country.
Background
Antibodies to human immunodeficiency virus (HIV) have been detected in most patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex (ARC), and in many asymptomatic individuals belonging to high-risk groups. Enzyme-linked immunosorbent assays (ELISA) are widely used to screen human blood and plasma samples for the presence of these HIV antibodies. However, since false-positive reactions have frequently been observed with current ELISA tests, it is strongly recommended to confirm repeatedly reactive samples by use of other reliable techniques (such as the INNO-LIA™ HIV I/II Score). Recombinant proteins and synthetic peptides from HIV-1 and HIV-2, and a synthetic peptide from HIV-1 group O, are coated as discrete lines on a nylon strip with plastic backing. The INNO-LIA™ HIV I/II Score assay contains sequences derived from HIV-O sequences to allow the optimal detection of infections caused by this group of viruses. To allow the broad spectrum detection of all HIV infections, the INNO-LIA™ HIV I/II Score assay also contains separate lines for the differentiation of HIV-1 and HIV-2 infections. This is important, as HIV-2 is less virulent, resulting in a better prognosis for the patient.